Calling It: These Will Be the Biggest Supplement Trends

by Editor
Published: Updated:

2023 UPDATE
Our article was published in December 2019, and we were curious to see how many of these wellness supplement trends hit the mark. So we asked our ChatGPT to weigh in – here’s what they said!

As an AI language model, I don’t have direct access to the internet or the ability to browse specific websites. However, I can provide you with information based on my training up until September 2021 and provide you with an overview of some supplement trends that were popular in 2020 and have continued to gain traction.

1. Immune-boosting supplements: Given the COVID-19 pandemic, there has been a heightened interest in supplements that support immune health. Vitamins C and D, zinc, elderberry, and various herbal extracts like echinacea and astragalus are among the commonly used immune-boosting supplements.

2. Collagen supplements: Collagen has gained popularity for its potential benefits for skin health and joint support. Collagen supplements come in various forms, such as powders, capsules, and drinks.

3. Adaptogens: Adaptogens are natural substances that help the body adapt to stress and promote balance. Popular adaptogenic herbs include ashwagandha, rhodiola, holy basil (tulsi), and reishi mushroom. These supplements are often used to support stress management and overall well-being.

4. Probiotics: Probiotic supplements, which contain beneficial bacteria, have continued to be popular in 2020 and beyond. They are commonly used to support gut health and promote a balanced microbiome.

5. CBD supplements: Cannabidiol (CBD) gained significant attention in recent years. CBD supplements are derived from hemp and are often used for relaxation, stress relief, and potential anti-inflammatory effects. However, regulations and acceptance of CBD products can vary by region.


We’re all curious about the supplement trends we can look forward to for better health. That’s why we consulted industry leader Dr. Traj Nibber, a formulator in the supplement industry for 30 years, to get the inside scoop.

Dr. Nibber, also the Founder and CEO of Advanced Orthomolecular Research, has shared his predictions for the hottest supplement trends of 2020.

Pill Fatigue

A downtrend in traditional delivery methods, we’re going from capsules and hard tablets to new delivery systems such as powders, liquids, candies, and different tastable forms.

Specifically, we will see increases in chewables and unique deliveries such as jellies, fizzing candies, healthier gummies, and easy squeeze pouches, which might have people questioning: is this food or a supplement?

Goodbye CBD, Hello PEA

PEA is a fatty acid from coconut, lecithin and peanuts, which is also naturally produced by the body during times of disease and stress.

Unlike the current trend of CBD for treating pain and inflammation, PEA is a well-researched molecule that has not shown to have issues with safety (for children or seniors) and avoids the common stigma associated with cannabis.

Probiotics, Pre-Biotics, Now…Post Biotics

Postbiotics are probiotics that are heat killed yet retain (sometimes even more potent) all the properties of the live probiotic.

The big advantage is that most probiotics have a hard time meeting label claims when tested for the final finished product, so manufacturers resort to putting in large amounts of overages.

Postbiotics avoid this issue, and manufacturers only need to put in exact amounts. Plus, the product will be shelf-stable – great for travel.

Shining Saffron

Saffron will shine brightly. Saffron is one of the best for depression and anxiety, with good clinical research. This herb is revered, but due to the high cost is also vulnerable to adulteration. So, buyers, beware.

Eye Health

As screen time continues to increase, eye health is a growing concern. Eye health products (Lutein and zeaxanthin are some assumed top performers) will find a way into the children’s market as phones, tablets, computers, and video games continue to drive screen time.

Calorie Restriction Mimetics (CRMs)

Move over intermittent fasting … new molecules are being researched that increase the body’s ability to turn on the same genes that fasting and caloric restriction does. Molecules like NAD+, nicotinamide riboside and others like spermidine will come to the forefront.

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